Abstract: Objective This study focused on the systematic literature measurement and visual analysis of treating COVID-19 with combined Chinese and Western medicine to explore the development status，research hot spots and trends，and cutting-edge dynamics. It provides data，information support，and development references for treating COVID-19 with combined Chinese and Western medicine. Methods Three major databases of China National Knowledge Infrastructure （CNKI）， Wanfang Data， and China Science and Technology Journal Database were used as data sources to retrieve the relevant literature on the combined Chinese and Western medicine for the treatment of COVID-19 from March 2019 to March 2022. Statistical analysis was performed using bibliometric methods and CiteSpace software. Visual analysis was performed on publishing trends，research institution cooperation， author cooperation， keyword co-occurrence and clustering， and research hotspots. Results A total of 476 articles were included in this study，with the largest number published in 2020. Statistical analysis of published units showed that the cooperative relationship between institutions was discrete，indicating that the research on treating novel coronavirus with combined Chinese and western medicine was extensive. Hot spots in the research were mainly reflected in four aspects：coronavirus，diagnosis and treatment plan， combined Chinese and Western medicine，and epidemic prevention and control. Conclusion The research theme of treating COVID-19 with combined Chinese and Western medicine dynamically changes with the epidemic development，which is guided by clinical efficacy. It mainly focuses on the formulation of diagnosis and treatment plans. The cooperation between authors and institutions is insufficient，and communication needs to be further strengthened.

Key words: COVID-19, combination of Chinese and Western medicine, visual analysis, CiteSpace