Abstract: Objective To study the clinical predictive value of Cystatin C（Cys C）level to coronary artery stenosis degree of aged Coronary Heart Disease（CHD） . Methods Retrospectively analyzed 185 cases of aged CHD diagnosed with coronary angiography. According to the results of coronary angiography，185 cases were divided into single lesion group（89 cases）and multivessel lesions group（96 cases） ，detected Cys C level and graded Gensini score in all selected cases，analyzed the difference of level of Cys C，also the correlation of Cys C level and the coronary artery Gensini score in two groups. Results （1） The Cys C levels in multivessel lesions group（ （1. 55±0. 32） mg/L）was obviously higher than that in single lesion group（ （1. 28 ± 0. 20）mg/L） （P<0. 01） . （2）In two groups，the Cys C levels were positive correlated with Gensini score（multivessel leisions group，r=0. 78，P<0. 01；single lesion group，r=0. 75，P<0. 01） . Conclusion With Cys C level detecting，the coronary artery lesion degree can be predicted，as the increasing of Cys C level，the artery stenosis degree become more seriously.

Key words: Cystatin C, coronary artery stenosis, Gensini score, aged patient