Abstract: Objective To explore the clinical application effect of the Herbert screw for the treatment of medial malleolus fracture. Methods Selects 38 cases of Herbert screw for the treatment of medial malleolus fracture from July 2011 to August 2013 in orthopedics department in the affiliated hospital of Jianghan University，patients were followed up for 3-6 months，according to the American Society for Ankle Surgery（AOFAS）score standard for curative effect evaluation. Results Finally 36 patients completed the study，2 cases missed，there were 25 excellent，8 well，3 satisfaction，good rate 91. 67% . Conclusion Herbert screw for the treatment of medial malleolus fracture has achieved good effect，for the treatment of medial malleolus fracture，it provides a new choice and it is worthy for popularizing.