江汉大学学报(自然科学版) ›› 2023, Vol. 51 ›› Issue (6): 40-46.doi: 10.16389/j.cnki.cn42-1737/n.2023.06.006

• 医学 • 上一篇    

脂肪胰的临床研究进展

丁三秀1 ,丁祥武*2   

  1. 1. 江汉大学 医学部,湖北 武汉 430056;2. 武汉市第四医院 消化内科,湖北 武汉 430030
  • 发布日期:2023-12-25
  • 通讯作者: 丁祥武
  • 作者简介:丁三秀(1993— ),女,硕士生,研究方向:消化系统疾病。

Clinical Research Progress of Fatty Pancreas

DING Sanxiu ,DING Xiangwu   

  1. 1. School of Medicine,Jianghan University,Wuhan 430056,Hubei,China;2. Department of Gastroenterology, Wuhan Fourth Hospital,Wuhan 430030,Hubei,China
  • Published:2023-12-25
  • Contact: DING Xiangwu

摘要: 脂肪替代和脂肪浸润都可导致脂肪胰,近年来关于脂肪胰的研究逐渐增多,但其发病机 制,诊断标准仍不明确。胰腺内的脂肪堆积会影响代谢功能从而增加患糖尿病、非酒精性脂肪 肝、冠心病、胰腺炎、胰腺癌及术后胰瘘等疾病的风险。脂肪胰的临床表现不典型,因此临床上多 采 用 超 声 、计 算 机 断 层 扫 描(CT)、磁 共 振(MR)等 对 其 诊 断 ,目 前 超 声 内 镜(EUS)和 定 量 CT (QCT)对脂肪胰的诊断也有了新的进展。脂肪胰多采用减重和降脂药物治疗,其预后尚不清 楚。就国内外对脂肪胰的流行病学、相关疾病、诊断和治疗的研究进展进行阐述,为探究脂肪胰 的诊断、病情程度评估及干预病程提供新的思路。

关键词: 脂肪胰, 流行病学, 诊断, 治疗

Abstract: Both fat replacement and fat infiltration can lead to fatty pancreas(FP),and in recent years,research on fatty pancreas has gradually increased,but its pathogenesis and diagnostic criteria are still unclear. Fat accumulation in the pancreas can affect metabolic function and increase the risk of diabetes,non-alcoholic fatty liver disease,coronary heart disease,pancreatitis,pancreatic cancer,and postoperative pancreatic fistula. The clinical manifestations of the fatty pancreas are not typical,so ultrasound,computed tomography (CT),magnetic resonance(MR),and other techniques are used to diagnose it in clinical practice. At present,endoscopic ultrasound(EUS)and quantitative CT(QCT)have also made new progress in the diagnosis of fatty pancreas. FP is mostly treated with weightreducing and lipid-lowering drugs,but its prognosis is unclear. This article reviewed the research progress on the epidemiology,related diseases,diagnosis,and treatment of FP at home and abroad,to provide new ideas for exploring the diagnosis,evaluation of disease severity,and intervention of the disease course of FP.

Key words: fatty pancreas, epidemiology, diagnosis, treatment

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