Abstract: ObjectiveIn search of effective and less side－effective treatment protocols of deficient hyperactivity disorder (ADHD). Methods120 children met the inclusive and exclusive criterion were randomized into 3 groups40 cases in Group A with medications combined with behavior therapy, 40 cases in Group B with medications combined with acupuncture therapy and 40 cases in Group C with medications alone. The outcomes of clinical efficacy, Conners index of hyperactivity (CIH) and adverse drug reaction among the three groups were compared respectively. ResultsSignificant differences were found in the clinical efficacy among 3 groups before and after treatment, and there were significant differences between Group A and C. The CIH scores of 3 groups all showed significantly reduction before and after treatment, significant differences were found in post－treatment scores of CIH among 3 groups, especially Group A vs C and Group B vs C. Adverse drug reaction was observed in all 3 groups, and Group B with less adverse drug reaction than Group A and C. ConclusionThe 3 interventions all have the effect of reducing the symptoms of ADHD. The behavior therapy can obviously increase the clinical effect of Methylphenidate, while acupuncture can obviously reduce the adverse drug reaction of Methylphenidate. It should be combined with behavior therapy, acupuncture and medications, in order to increase the validity and safety of the intervention on ADHD.

Key words: attention deficit hyperactivity disorder, methylphenidate hydrochloride, behavior therapy, acupuncture therapy