江汉大学学报(自然科学版) ›› 2015, Vol. 43 ›› Issue (4): 376-381.

• 医学 • 上一篇    下一篇

菊花挥发油主要成分对肿瘤抗性的研究进展

周晓叶a, 蒋细旺b, 镇鸿燕*a   

  1. 江汉大学 a. 医学院; b. 生命科学学院, 湖北 武汉 430056
  • 出版日期:2015-08-28 发布日期:2015-08-13
  • 通讯作者: 镇鸿燕
  • 作者简介:周晓叶( 1989—), 女, 硕士生, 研究方向: 天然产物药理。
  • 基金资助:
    武汉花卉( 菊花)工程技术研究中心项目( 2013021005010466); 武汉市教育局项目( CXY201403)

Progress of Antineoplastic Activities of Chrysanthemum Essential Oils′ Main Ingredients on Multiple Tumor Cells

ZHOU Xiaoyea, JIANG Xiwangb, ZHEN Hongyan*a   

  1. a. School of Medicine; b. School of Life Science, Jianghan Univiersity, Wuhan 430056, Hubei, China
  • Online:2015-08-28 Published:2015-08-13

摘要: 菊花作为药食同源植物, 含有多种化学成分, 具有多种药理活性。 菊花中含有挥发油、 黄酮、 绿原酸、 生物碱、 多糖、 氨基酸等化学成分, 现代药理研究证明菊花具有多种功效, 如抗癌、 抗氧化、 抗炎、 抗病毒、 抗菌等,并对心血管、 免疫系统、 神经系统有一定作用 。 菊花成分中的挥发油, 证实能够对多种癌症有抵抗功效, 对近几年菊花挥发油中的主要成分β-榄香烯、 小白菊内酯及菊花三萜烯二醇和三醇、 α-甜没药萜醇、 棕榈酸等的抗癌功效研究进行综述, 以明确挥发油成分的抗癌潜力 。

关键词: 菊花, 挥发油, 萜类, 抗癌, 小白菊内酯, β-榄香烯

Abstract: The chrysanthemum, a medicine-food homology plant, has various chemical composition and pharmacologic activities. The chemical composition of chrysanthemum contain essential oils, flavonoids, chlorogenic acid, alkaloid, polysaccharides, amino acids and others. Modern pharmacological researches manifest that chrysanthemum has the multiple activities, such as anticancer, antioxidant, antiinflammatory, antivirus, antimicrobial effects and so on. In addition, it has effects on cardiovascular system, immune system and nervous system. Essential oils, one of the most significant elements, are testi? fied as anticancer potentiality. The anticancer efficacy of the main composition of chrysanthemum essential oils such as elemene, parthenolide and others are summarized, to make clear the anticancer potentiality.

Key words: chrysanthemum, essential oils, terpenes, anticancer, parthenolide, β-elemene

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