内固定联合抗骨质疏松药物治疗老年人桡骨远端骨折的疗效观察

doi:10.16389/j.cnki.cn42-1737/n.2018.01.016

江汉大学学报（自然科学版） ›› 2018, Vol. 46 ›› Issue (1): 83-86.doi: 10.16389/j.cnki.cn42-1737/n.2018.01.016

内固定联合抗骨质疏松药物治疗老年人桡骨远端骨折的疗效观察

李建海¹，刘涛¹，逄健飞¹，刘焱¹，黄念芳²，熊南山^*1

1. 中国人民解放军第457医院，湖北武汉 430012；2. 江汉大学医学实验中心，湖北武汉 430056

出版日期:2018-02-28 发布日期:2018-02-03
通讯作者: 熊南山
作者简介:李建海（1974—），男，主治医师，研究方向：肌肉骨骼疾患与预防医学。

Curative Effect of Internal Fixation Combined Anti-Osteoporosis Medicine on Distal Radius Fractures in Aged Patients

LI Jianhai¹, LIU Tao¹, PANG Jianfei¹, LIU Yan¹, HUANG Nianfang², XIONG Nanshan^*1

1. The 457th Hospital of PLA, Wuhan 430012, Hubei，China；2. Medical Experimental Center，Jianghan University，Wuhan 430056，Hubei，China

Online:2018-02-28 Published:2018-02-03
Contact: XIONG Nanshan

摘要/Abstract

摘要： 目的 观察桡骨远端锁定加压接骨板（LCP）联合抗骨质疏松药物治疗老年骨质疏松性桡骨远端骨折的临床疗效。方法 对2010年4月至2015年4月在解放军第457医院骨科进行治疗的90例老年骨质疏松性桡骨远端骨折患者进行回顾分析，其中45例应用LCP + 抗骨质疏松药物治疗（试验组），45例应用单纯LCP治疗（对照组）。从骨折愈合时间、骨折部位骨密度值（BMD）和关节功能评价等方面进行比较。结果 90例患者均获随访，平均随访时间16. 5 个月。试验组骨折愈合时间（10. 5 ± 1. 4）周，低于对照组（14. 3 ± 2. 1）周；按照Gartland-Werley腕关节功能评分，试验组优良率为93. 3%，对照组88. 8%，其疗效比较差异无统计学意义（ P ＞0. 05）。试验组BMD 术前（0. 618 ± 0. 105）g/cm²，术后药物治疗3 个月后为（0. 680 ± 0. 092）g/cm²，BMD值明显提高，差异有统计学意义（ P ＜0. 05）；对照组BMD 术前（0. 621 ± 0. 085）g/cm²，术后3 个月为（0. 627 ± 0. 089）g/cm²，差异无统计学意义（ P ＞0. 05）。结论 与单纯LCP 治疗相比，联合抗骨质疏松药物治疗老年骨质疏松性桡骨远端骨折具有固定可靠、骨折愈合时间短、疗效显著的优点，结合适时积极的康复锻炼是目前治疗该类骨折较为适用的方法。

关键词: 骨质疏松, 桡骨远端骨折, 内固定, 锁定加压接骨板, 药物治疗

Abstract: Objective To observe clinical curative effect of radial distal locking compression plate（LCP）combined anti-osteoporosis medicine on treatment of senile osteoporosis distal radius fractures.Methods In April，2010 to April，2015 in the department of orthopedics in the 457th Hospital of PLA, 90 cases of elderly patients with osteoporotic fracture of the distal radius were retrospective analysed, including 45 cases treated with LCP + anti- osteoporosis medicine（experimental group）, 45 cases treated with LCP alone（control group）. The fracture healing time, the fracture bone mineral density（BMD）values and the joint function assessment were comparatively analysed. Results 90 patients all have been followed up, with an average follow-up time of 16. 5 months. The fracture healing time of the experimental group（10. 5 ± 1. 4）weeks was less than that of the control group（14. 3 ± 2. 1）weeks；according to the Gartland - Werley wrist joint function score, the excellent rate of the experimental group was 93. 3% and that of the control group was 88. 8%, the efficacy differences were not statistically significant（ P >0. 05）. Preoperative BMD in the experimental group was（0. 618+0. 105）g/cm², post?operative medication for three months was（0. 680+0. 092）g/cm², BMD values increased significantly, the differences were statistically significant（ P <0. 05）；preoperative BMD in the control group was（0. 621+ 0. 085）g/cm², postoperative three months was（0. 627+0. 089）g/cm², the differences were not statistically significant（ P >0. 05 ）. ObjectiveConclusion Compared with pure LCP treatment, the LCP combined anti-osteoporosis medicine in treatment of senile osteoporotic distal radius fractures has reliable fixation, the fracture healing time is short, the curative effect is distinct, the method combined with positive rehabilitation exercise timely is applicable for treatment of such fractures.

Key words: osteoporosis, fracture of distal radius, internal fixation, locking compression plate（LCP）, medicine

中图分类号:

R683.41

李建海，刘涛，逄健飞，刘焱，黄念芳，熊南山. 内固定联合抗骨质疏松药物治疗老年人桡骨远端骨折的疗效观察[J]. 江汉大学学报（自然科学版）, 2018, 46(1): 83-86.

LI Jianhai, LIU Tao, PANG Jianfei, LIU Yan, HUANG Nianfang, XIONG Nanshan. Curative Effect of Internal Fixation Combined Anti-Osteoporosis Medicine on Distal Radius Fractures in Aged Patients[J]. Journal of Jianghan University(Natural Science Edition), 2018, 46(1): 83-86.

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内固定联合抗骨质疏松药物治疗老年人桡骨远端骨折的疗效观察

Curative Effect of Internal Fixation Combined Anti-Osteoporosis Medicine on Distal Radius Fractures in Aged Patients

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