壬基酚对泥鳅肝脏组织的CAT、 T-SOD活性的影响

江汉大学学报（自然科学版） ›› 2014, Vol. 42 ›› Issue (5): 87-90.

壬基酚对泥鳅肝脏组织的CAT、 T-SOD活性的影响

王延琨，游浩，梁勇，叶超，祝常青，刘燕群^*

江汉大学医学院，湖北武汉 430056

出版日期:2014-10-25 发布日期:2014-11-11
通讯作者: 刘燕群
作者简介:王延琨（1994—），男，研究方向：公共卫生。
基金资助:
国家自然科学基金项目（20977041）；湖北省高等学校优秀中青年科技创新团队项目（T201224）；武汉市创新人才开发资金重大创新活动专项资助［2011］ 415号；武汉市人才工程入选人员科研项目择优资助（2012）；湖北省自然科学基金（2012）；江汉大学大学生科研项目（2013）

Influence of Nonylphenol on CAT and T-SOD Enzyme Activities in Loach Fish Liver

WANG Yankun, YOU Hao, LIANG Yong, YE Chao, ZHU Changqing, LIU Yanqun^*

School of Medicine, Jianghan University, Wuhan 430056, Hubei, China

Online:2014-10-25 Published:2014-11-11
Contact: LIU Yanqun
About author:刘燕群（1968—），女，教授，博士，研究方向：环境卫生。E-mail： nanyan85@126.com

摘要/Abstract

摘要： 目的 探讨壬基酚对泥鳅肝脏组织的CAT、 T-SOD活性的影响。方法 将泥鳅暴露于不同浓度的壬基酚溶液中，壬基酚分别为50、 200、 500、 1 000 μg/L，于6h测定其总超氧化物歧化酶（T-SOD）及过氧化氢酶（CAT）的活性。结果 低浓度的壬基酚对SOD、 CAT活性有诱导作用，随着壬基酚浓度的增加， CAT、T-SOD活性随着壬基酚浓度的增大而受到抑制。结论 泥鳅肝脏组织中的 CAT和 T-SOD活性与水中壬基酚的浓度直接相关，随着壬基酚浓度的升高， CAT和T-SOD的活性表现均为诱导-抑制规律，泥鳅肝脏组织中CAT和T-SOD的活性均对壬基酚的早期污染具有指示作用。

关键词: 壬基酚, 泥鳅, CAT, T-SOD, 肝脏组织

Abstract: Objective To study the influence of nonylphenol on CAT and T-SOD enzyme activities in loach liver tissue. Methods The loaches were exposed in different concentration of nonylphenol. The concentration of nonylphenol were 50，200，500，1 000 μ g/L. Determined the activities of T-SOD and CAT after 6 hours. Results Low concentration of nonylphenol has an inducing effect on the activities of T-SOD and CAT in loach liver tissue, as the concentration of nonylphenol increased, the activities of CAT and T-SOD was restrained. Conclusion The concentration of nonylphenol in water is direct related to the CAT and T-SOD activities in the liver tissue of loach, as concentration of nonylphenol increasing, the CAT and T-SOD activities are all expressed in an inducing-repressing manner. The CAT and T-SOD activities have indicative function for early pollution of nonylphenol.

Key words: nonylphenol, loach, CAT, T-SOD, liver tissue

中图分类号:

R114-33

王延琨，游浩，梁勇，叶超，祝常青，刘燕群. 壬基酚对泥鳅肝脏组织的CAT、 T-SOD活性的影响[J]. 江汉大学学报（自然科学版）, 2014, 42(5): 87-90.

WANG Yankun, YOU Hao, LIANG Yong, YE Chao, ZHU Changqing, LIU Yanqun. Influence of Nonylphenol on CAT and T-SOD Enzyme Activities in Loach Fish Liver[J]. Journal of Jianghan University(Natural Science Edition), 2014, 42(5): 87-90.