低强度脉冲超声和低频电磁场联合治疗兔桡骨骨折中外骨痂和骨折线的影像评价

江汉大学学报（自然科学版） ›› 2014, Vol. 42 ›› Issue (5): 53-57.

低强度脉冲超声和低频电磁场联合治疗兔桡骨骨折中外骨痂和骨折线的影像评价

钟守昌¹，黄丽霞¹，李长雷¹，柴燕²

1.江汉大学医学院，湖北武汉 430056； 2.武汉市第八医院，湖北武汉 430010

出版日期:2014-10-25 发布日期:2014-11-11
作者简介:钟守昌（1964—），男，副教授，硕士，研究方向：医学生物工程。
基金资助:
武汉市科技局国际合作研究项目（200870834408）

Image Evaluation of Low-intensity Pulsed Ultrasound and Low Freguency Electromagnetic Fields Combined Treatment on External Callus and Fracture Line of Rabbit Radius Fracture

ZHONG Shouchang ¹ ， HUANG Lixia ¹ ， LI Changlei ¹ ， CHAI Yan ²

1. School of Medicine， Jianghan University， Wuhan 430056， Hubei， China；2. The Eighth Hospital of Wuhan， Wuhan 430010， Hubei， China

Online:2014-10-25 Published:2014-11-11

摘要/Abstract

摘要： 目的 探讨低强度脉冲超声与低频电磁场联合作用促进骨折愈合的效果。方法 对 40只普通级成年健康日本大耳白兔进行前腿双侧桡骨中段横断面骨折建模，并将实验兔随机分为Ⅰ _a 、 Ⅰ _b 和Ⅱ _a 、 Ⅱ _b4个组，每组10只。Ⅰ _a 和Ⅱ _a 左侧进行低强度脉冲超声和低频电磁场联合治疗（U组），右侧仅进行低频电磁场治疗（E组）； Ⅰ _b 和Ⅱ _b 左侧仅进行低强度脉冲超声治疗（B组），右侧进行假治疗作为实验对照（C组）。低强度脉冲超声治疗强度为40mW/cm ² ，每天1次治疗20min，低频电磁场强度0.9mT，每天1次治疗40min。Ⅰ_a 、 Ⅰ _b 组治疗2周和Ⅱ _a 、 Ⅱ _b 治疗4周后，采用X线片指标评价骨折愈合情况。结果 X线片评分半定量分析表明，不论治疗2周还是治疗4周，U、 B、 E 3组骨折愈合速度明显快于与实验对照C组（P < 0. 05），但U、 B、E组之间的差异无统计学意义（P > 0. 05）。结论 低强度脉冲超声和低频电磁场体外治疗都可以通过影响骨折愈合的愈合期和塑形期而促进骨折愈合，但两者叠加使用加速促进骨折愈合的疗效并不明显。

关键词: 低强度脉冲超声, 低频电磁场, 联合治疗, 外骨痂和骨折线

Abstract: Objective To investigate the combined effects of low-intensity pulsed ultrasound and low frequency electromagnetic fields in promoting fracture healing. Methods 40 ordinary healthy grown Japanese rabbits were prepared forelegs bilateral radial middle cross-section fracture model and the rabbits werer and only divided into four groups ： Ⅰ _a ，Ⅰ _b and Ⅱ _a ，Ⅱ _b ,each consists of 10.Left side of rabbits from groupⅠ _a and Ⅱ _a was carried combined treatment of the low-intensity pulsedultrasound and low frequency electromagnetic fields（group U），on the right side with only the lowfrequency electromagnetic field therapy（group E）；Left side of rabbits from groupⅠ _b and Ⅱ _b only for low-intensity pulsed ultrasound therapy（ group B），and right side carried out sham treatment as control group（group C） . The intensity of ultrasound treatment is 40mW/cm ² ，20 minutes a day of treatment. The intensity of low frequency electromagnetic field is 0.9mT. 40minutes a day of treatment. X-ray index evaluation of fracture healing was taken after two weeks treatment of groupⅠ _a ，Ⅰ _b and 4weeks treatment of group Ⅱ _a ，Ⅱ _b . Results Semiquantitative analysis of X-ray film evaluation showed that regardless of 2weeks or 4weeks treatment ，fracture healing of group U，B，E are significantly faster than the control group C（P<0.05），but no significant difference among group U，B，E（P>0.05） . Conclusion The low-intensity pulsed ultrasound and low frequency electromagnetic fields can promote fracture healing by affecting fracture healing period and modeling period，but the effect of combination of the two treatment to accelerate fracture healing is not obvious.

Key words: low-intensity pulsed ultrasound, low frequency electromagnetic fields, combination treatment, external callus and fracture line

中图分类号:

钟守昌，黄丽霞，李长雷，柴燕. 低强度脉冲超声和低频电磁场联合治疗兔桡骨骨折中外骨痂和骨折线的影像评价[J]. 江汉大学学报（自然科学版）, 2014, 42(5): 53-57.

ZHONG Shouchang ， HUANG Lixia ， LI Changlei ， CHAI Yan. Image Evaluation of Low-intensity Pulsed Ultrasound and Low Freguency Electromagnetic Fields Combined Treatment on External Callus and Fracture Line of Rabbit Radius Fracture[J]. Journal of Jianghan University(Natural Science Edition), 2014, 42(5): 53-57.