关键词: 线粒体代谢, 免疫细胞, 氧化磷酸化, 脂肪酸氧化, 氨基酸代谢

Abstract: As an important organelle，mitochondria，the site of cellular metabolic substance synthesis and energy production，are involved in many important biological processes，such as cell proliferation，differentiation，and apoptosis. Immune cells are the main components of the immune system and have an important impact on maintaining the immune homeostasis of the body. In recent years，more studies have revealed the importance of mitochondrial metabolism in immune cells，e.g. ，mitochondria can release signals such as mitochondrial DNA and mitochondrial reactive oxygen species to regulate immune cell activation， differentiation，and function. Changes in mitochondrial metabolism may be the underlying cause of immunocytopenia or immune cell damage. Here， we reviewed the role of mitochondrial metabolism in immune cells and provided an overview of current research progress on the effects of mitochondrial metabolism on immune cells.

Key words: mitochondrial metabolism, immune cells, oxidative phosphorylation, fatty acid oxidation, amino acid metabolism